SCHEMBL56824

SCHEMBL56824

O=C1c2[c]cc[c]c2C(=O)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 4/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
MAPT P10636 4/20 0.52
S100A4 P26447 4/20 0.52
MAOA P21397 4/20 0.52
APAF1 O14727 3/20 0.52
POLB P06746 3/20 0.52
RAB9A P51151 3/20 0.52
KDM4E B2RXH2 3/20 0.52
TDP2 O95551 2/20 0.52
LMNA P02545 2/20 0.52
BLM P54132 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
MAPK1 P28482 2/20 0.52
CES2 O00748 1/20 0.52
TERT O14746 1/20 0.52
NPC1 O15118 1/20 0.52
PLIN1 O60240 1/20 0.52
S1PR4 O95977 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5506572 0.83 CDC25B (0.55) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL18844 0.83 S100A4 (0.52) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL136078 0.83 CDC25B (0.55) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL3673942 0.79 CDC25B (0.41) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL2077973 0.78 MEN1 (0.55) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL9503298 0.77 MEN1 (0.35) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL8658090 0.75 ALDH1A1 (0.47) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL3983265 0.75 ADORA2A (0.59) CDC25BMEN1KMT2AMAPTS100A4
SCHEMBL4861795 0.74 CDC25B (0.55) CDC25BMEN1KMT2AMAPTS100A4
Anthraquinone SCHEMBL1901249 0.73 MEN1 (1.00) CDC25BMEN1KMT2AMAPTS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118184562-A Preparation method of (R) -4-propyl pyrrolidine-2-ketone 浙江京新药业股份有限公司 2024-06-14 CN claimed
CN-118184536-A Preparation method of formoterol 山东新时代药业有限公司 2024-06-14 CN claimed
CN-110724040-B Method for synthesizing iodo-trifluoromethoxyl compound 南开大学 2020-11-27 CN claimed
CN-111763202-A Synthetic method of hydrogenated quinine (anthraquinone-1, 4-diyl) diether 上海茂晟康慧科技有限公司 2020-10-13 CN claimed
CN-110724040-A Method for synthesizing iodo-trifluoromethoxyl compound 南开大学 2020-01-24 CN claimed
EP-1209142-B1 Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols COUNCIL SCIENT IND RES (IN) 2004-05-26 EP claimed
EP-1209142-A1 Preparation of new layered double hydroxides exchanged with osmate for asymmetric dihydroxylation of olefins to vicinal diols COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-05-29 EP claimed
US-6387033-B1 CIS ISOMERS FOR HYDROXYLATION OF OLEFINS COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-05-14 US claimed
EP-0293651-B1 Dicyanovinyl-substituted furan derivatives, process for their preparation, and their use SUEDZUCKER AG (DE) 1994-02-02 EP claimed
CN-118184562-A Preparation method of (R) -4-propyl pyrrolidine-2-ketone 浙江京新药业股份有限公司 2024-06-14 CN disclosed
CN-118184536-A Preparation method of formoterol 山东新时代药业有限公司 2024-06-14 CN disclosed
CN-116917282-A Amide derivatives and use thereof 成都百裕制药股份有限公司 2023-10-20 CN disclosed
CN-116635373-A Amide derivatives and use thereof 成都百裕制药股份有限公司 2023-08-22 CN disclosed
CN-116635374-A Amide derivatives and use thereof 成都百裕制药股份有限公司 2023-08-22 CN disclosed
US-5252757-A Dicyanoazulenyl and dicyanovinyl substituted furan SUDDEUTSCHE ZUCKER-AKTIENGSELLSCHAFT (DE) 1993-10-12 US disclosed
US-5091538-A DICYANOVINYLSUBSTITUTED FURAN DERIVATIVES SUDDEUTSCHE ZUCKER-AKTIENGESELLSCHAFT (DE) 1992-02-25 US disclosed
US-5053302-A Photosensitivity, durability FUJI PHOTO FILM CO., LTD. (JP) 1991-10-01 US disclosed
US-4892899-A Novel compositions based on tetrachloroisoindolinone pigments CIBA-GEIGY CORPORATION (US) 1990-01-09 US disclosed
US-4865650-A FOR COLORING HIGH MOLECULAR WEIGHT COMPONENTS; PAINTS; RHEOLOGY, LUSTER CIBA-GEIGY CORPORATION (US) 1989-09-12 US disclosed
US-3978062-A ORGANIC PIGMENTS SANDOZ LTD. (CH) 1976-08-31 US disclosed