Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | EBP | Q15125 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505419 | 0.90 | NCEH1 (0.45) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9505418 | 0.89 | SIGMAR1 (0.43) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9503551 | 0.86 | SIGMAR1 (0.41) | SIGMAR1EBPTMEM97 | |
| SCHEMBL10956576 | 0.84 | TRPV1 (0.53) | SIGMAR1EBPTMEM97 | |
| Bromide SCHEMBL10960279 | 0.83 | KDM4E (0.54) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9503683 | 0.80 | DRD2 (0.64) | — | |
| Hydrochloric Acid SCHEMBL9507149 | 0.79 | DRD2 (0.63) | — | |
| SCHEMBL9506536 | 0.79 | SIGMAR1 (0.48) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9503522 | 0.74 | SIGMAR1 (0.52) | SIGMAR1EBPTMEM97 | |
| SCHEMBL9503329 | 0.72 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321967-B1 | COMPOUNDS ACTIVE ON THE CARDIOVASCULAR SYSTEM | ZAMBON GROUP S.p.A. (IT) | 1993-07-28 | — | — | EP | disclosed |
| EP-0321967-A2 | Compounds active on the cardiovascular system | ZAMBON GROUP S.p.A. (IT) | 1989-06-28 | — | — | EP | disclosed |