Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 8/20 | 0.55 |
| ▸ | MMP2 | P08253 | 7/20 | 0.55 |
| ▸ | MMP3 | P08254 | 7/20 | 0.55 |
| ▸ | MMP7 | P09237 | 7/20 | 0.55 |
| ▸ | MMP13 | P45452 | 7/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | STS | P08842 | 1/20 | 0.51 |
| ▸ | MMP9 | P14780 | 7/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503295 | 0.91 | NR1H2 (0.48) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL13106876 | 0.91 | NR1H2 (0.48) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL9006094 | 0.90 | STS (0.49) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL9506253 | 0.89 | NR1H2 (0.50) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL9507059 | 0.89 | NR1H2 (0.50) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL9505085 | 0.88 | NR1H2 (0.50) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL30638141 | 0.87 | MMP2 (0.52) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL9506352 | 0.84 | STS (0.53) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL30476456 | 0.83 | STS (0.48) | MMP1MMP2MMP3MMP7MMP13 | |
| SCHEMBL12267639 | 0.81 | NR1H2 (0.50) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289911-B1 | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |