Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.53 |
| ▸ | MMP1 | P03956 | 7/20 | 0.49 |
| ▸ | MMP3 | P08254 | 6/20 | 0.49 |
| ▸ | MMP7 | P09237 | 6/20 | 0.49 |
| ▸ | MMP13 | P45452 | 6/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.46 |
| ▸ | MMP8 | P22894 | 3/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.43 |
| ▸ | HRH2 | P25021 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504084 | 0.90 | NR1H2 (0.46) | STSMMP13ALDH1A1NR1H2HRH2 | |
| SCHEMBL9006196 | 0.89 | STS (0.52) | STSNR1H2HRH2HRH1 | |
| SCHEMBL9503238 | 0.89 | NR1H2 (0.46) | NR1H2TGFBR1 | |
| SCHEMBL10701160 | 0.89 | NR1H2 (0.46) | NR1H2TGFBR1 | |
| SCHEMBL9507014 | 0.89 | NR1H2 (0.46) | NR1H2TGFBR1 | |
| SCHEMBL9506263 | 0.87 | NR1H2 (0.48) | STSALDH1A1NR1H2TGFBR1 | |
| SCHEMBL30476456 | 0.86 | STS (0.48) | STSMMP1MMP3MMP7MMP13 | |
| SCHEMBL9503339 | 0.84 | MMP1 (0.55) | STSMMP1MMP3MMP7MMP13 | |
| SCHEMBL13662045 | 0.78 | CTSL (0.52) | ALDH1A1NR1H2 | |
| SCHEMBL30476480 | 0.76 | LIPE (0.45) | STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0289911-B1 | PYRROLIDINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-4916152-A | THROMBOXANE A2 ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-04-10 | — | — | US | disclosed |
| EP-0289911-A2 | Pyrrolidine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-11-09 | — | — | EP | disclosed |