Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.50 |
| ▸ | BCL9 | O00512 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MYOC | Q99972 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503446 | 0.89 | MGLL (0.48) | HSPB1BCL9CTNNB1ALDH1A1MAPK1 | |
| SCHEMBL15055286 | 0.81 | NPC1 (0.58) | HSPB1BCL9CTNNB1ALDH1A1MAPK1 | |
| SCHEMBL9082994 | 0.80 | HSPB1 (0.59) | HSPB1ALDH1A1MAPK1CYP3A4TSHR | |
| SCHEMBL15279922 | 0.80 | HSPB1 (0.59) | HSPB1ALDH1A1MAPK1CYP3A4TSHR | |
| SCHEMBL9497275 | 0.80 | HSPB1 (0.59) | HSPB1ALDH1A1MAPK1CYP3A4TSHR | |
| SCHEMBL4670068 | 0.80 | HSPB1 (0.59) | HSPB1ALDH1A1MAPK1CYP3A4TSHR | |
| SCHEMBL22540967 | 0.77 | ALDH1A1 (0.47) | BCL9CTNNB1ALDH1A1MAPK1HSD17B10 | |
| SCHEMBL4670457 | 0.77 | HSPB1 (0.51) | HSPB1ALDH1A1MAPK1CYP3A4TSHR | |
| SCHEMBL4787853 | 0.77 | ALDH1A1 (0.54) | ALDH1A1MAPK1HSD17B10POLBMEN1 | |
| SCHEMBL19387672 | 0.76 | BCL9 (0.50) | HSPB1BCL9CTNNB1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282254-B1 | DIAMINO COMPOUNDS AND LIQUID CRYSTAL ALIGNING FILMS | CHISSO CORPORATION (JP) | 1993-06-16 | — | — | EP | disclosed |
| US-5084557-A | Polyimides based on a 2,2-bis/p-/p-aminophenoxy/phenylalkane; a high pretilt angle for supertwisting nematic mode display cells | CHISSO CORPORATION (JP) | 1992-01-28 | — | — | US | disclosed |
| US-4864008-A | POLYIMIDE MONOMERS | CHISSO CORPORATION (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0282254-A2 | Diamino compounds and liquid crystal aligning films | CHISSO CORPORATION (JP) | 1988-09-14 | — | — | EP | disclosed |