Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.35 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503364 | 0.81 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1FFAR1 | |
| SCHEMBL9502590 | 0.80 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1FAAHPLA2G4BPLA2G4A | |
| SCHEMBL9427991 | 0.75 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1TRPV1DPP4 | |
| SCHEMBL9503373 | 0.72 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1FAAH | |
| SCHEMBL9856081 | 0.71 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1FAAHPLA2G4BPLA2G4A | |
| SCHEMBL9855785 | 0.71 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1FAAHPLA2G4BPLA2G4A | |
| SCHEMBL9504617 | 0.71 | CYSLTR2 (0.55) | CYSLTR2CYSLTR1FAAH | |
| SCHEMBL9505459 | 0.69 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1 | |
| SCHEMBL9856321 | 0.68 | CYSLTR2 (0.45) | CYSLTR2CYSLTR1PLA2G4B | |
| SCHEMBL8882396 | 0.67 | ASPH (0.50) | CYSLTR2CYSLTR1PLA2G4BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0548291-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-30 | — | — | EP | disclosed |
| WO-1992005156-A1 | PYRIDYLTHIO OR PYRIDYLOXY ALKANOIC ACIDS | SMITHKLINE BEECHAM CORPORATION (US) | 1992-04-02 | — | — | WO | disclosed |