Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505474 | 0.84 | KEAP1 (0.39) | MAPTGAACYP1A2KEAP1NFE2L2 | |
| SCHEMBL9504394 | 0.78 | HPGD (0.41) | MAPTGAACYP1A2ALDH1A1HPGD | |
| SCHEMBL9505297 | 0.78 | HPGD (0.41) | MAPTGAACYP1A2ALDH1A1HPGD | |
| SCHEMBL9503666 | 0.77 | HPGD (0.43) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL9503500 | 0.76 | HPGD (0.40) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL9507128 | 0.76 | MEN1 (0.42) | ALDH1A1HPGDKDM4EMEN1KMT2A | |
| SCHEMBL9503283 | 0.75 | HPGD (0.42) | MAPTALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL10697581 | 0.75 | KEAP1 (0.43) | GAACYP1A2KEAP1NFE2L2HPGD | |
| SCHEMBL10696448 | 0.73 | KEAP1 (0.44) | GAACYP1A2KEAP1NFE2L2MEN1 | |
| SCHEMBL6589388 | 0.72 | KEAP1 (0.61) | KEAP1NFE2L2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0336561-B1 | 2-PYRIDYLACETIC ACID DERIVATIVES, PREPARATIONS THEREOF, AND COMPOSITIONS CONTAINING THEM | SUNTORY LIMITED (JP) | 1993-07-28 | — | — | EP | claimed |