Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | ACACB | O00763 | 5/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786617 | 0.79 | NQO1 (0.52) | MAPTFFAR1LMNAATML3MBTL1 | |
| SCHEMBL6158908 | 0.79 | LTA4H (0.61) | MAPTLMNALTA4HNQO1SMN1; SMN2 | |
| SCHEMBL9502738 | 0.78 | LTA4H (0.55) | MAPTTTRACACBLMNAL3MBTL1 | |
| SCHEMBL1390870 | 0.77 | NQO1 (0.67) | MAPTLMNALTA4HNQO1SMN1; SMN2 | |
| SCHEMBL3726994 | 0.76 | ACACB (0.42) | MAPTACACBFFAR1SMN1; SMN2 | |
| SCHEMBL3716940 | 0.76 | ACACB (0.42) | MAPTACACBFFAR1GLASMN1; SMN2 | |
| SCHEMBL10088645 | 0.76 | CSNK2A1 (0.53) | MAPTTTRLMNAATML3MBTL1 | |
| SCHEMBL11611320 | 0.76 | MAPT (0.54) | MAPTLMNAATML3MBTL1LTA4H | |
| SCHEMBL11222733 | 0.74 | FFAR1 (0.66) | MAPTTTRFFAR1LMNAATM | |
| SCHEMBL17050830 | 0.74 | ACACB (0.52) | MAPTACACBL3MBTL1CSNK2A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186190-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-05-26 | — | — | EP | disclosed |
| EP-0132606-B1 | BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-10-07 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |
| US-4612323-A | Insecticidal and acaricidal derivatives of 1-benzylbenzimidazole | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-09-16 | — | — | US | disclosed |
| EP-0186190-A2 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0132606-A1 | Benzimidazole derivatives, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-02-13 | — | — | EP | disclosed |