Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 7/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | PARG | Q86W56 | 1/20 | 0.38 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3726994 | 0.82 | ACACB (0.42) | ACACBFFAR1MAPTSMN1; SMN2PARG | |
| SCHEMBL16954839 | 0.77 | SMN1; SMN2 (0.52) | MAPTGLASMN1; SMN2S1PR1S1PR3 | |
| SCHEMBL3716937 | 0.77 | AKR1C3 (0.51) | ACACBFFAR1MAPTPARGAKR1C3 | |
| SCHEMBL3726992 | 0.77 | ESRRA (0.53) | ACACBMAPTSMN1; SMN2PARGAKR1C3 | |
| SCHEMBL9503543 | 0.76 | MAPT (0.49) | ACACBFFAR1MAPTGLASMN1; SMN2 | |
| SCHEMBL3726441 | 0.76 | RAB9A (0.38) | ACACBMAPTSMN1; SMN2PARG | |
| SCHEMBL3720106 | 0.73 | SMN1; SMN2 (0.49) | ACACBGLASMN1; SMN2 | |
| SCHEMBL9379864 | 0.73 | SMN1; SMN2 (0.50) | MAPTSMN1; SMN2 | |
| SCHEMBL3786617 | 0.72 | NQO1 (0.52) | FFAR1MAPTSMN1; SMN2FFAR4 | |
| SCHEMBL17050832 | 0.72 | ACACB (0.57) | ACACBFFAR1MAPTFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010127208-A1 | INHIBITORS OF ACETYL-COA CARBOXYLASE | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-11-04 | — | — | WO | disclosed |