Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31277779 | 0.89 | TSHR (0.50) | LMNAMAPTL3MBTL1CA1CA2 | |
| SCHEMBL9420489 | 0.81 | GAA (0.53) | GAALMNASMN1; SMN2CA1CA2 | |
| SCHEMBL10758725 | 0.81 | TDP1 (0.46) | LMNAMAPTL3MBTL1CA1CA2 | |
| SCHEMBL10758730 | 0.79 | LMNA (0.46) | LMNAMAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL6201009 | 0.77 | MAOB (0.59) | GAAMAOBRAB9AMAOAMAPT | |
| SCHEMBL10755015 | 0.76 | LMNA (0.50) | LMNAMAPTL3MBTL1ALDH1A1HTT | |
| SCHEMBL25565579 | 0.76 | TSHR (0.52) | LMNARAB9ASMN1; SMN2L3MBTL1CA1 | |
| SCHEMBL1621831 | 0.76 | CA2 (0.55) | CA1CA2CA9CA4CA7 | |
| SCHEMBL18631331 | 0.75 | TSHR (0.50) | LMNAMAPTSMN1; SMN2CA1CA2 | |
| SCHEMBL5081823 | 0.74 | TSHR (0.62) | GAAMAOBLMNAMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344343-B1 | PROCESS FOR THE REGIOSPECIFIC SULFONATION OF 2-AMINO-NAPHTALENES SUBSTITUTED IN THE 5- OR 7-POSITION BY A FIBRE REACTIVE VS-GROUP, THE NOVEL 5-SULFO-SUBSTITUTED FIBER-REACTIVE 2-AMINO-NAPHTHALENE, AND FIBRE-REACTIVE AZO DYES THEREOF | HOECHST CELANESE CORPORATION (US) | 1993-04-21 | — | — | EP | disclosed |
| EP-0344343-A1 | Process for the regiospecific sulfonation of 2-amino-naphtalenes substituted in the 5- or 7-position by a fibre reactive vs-group, the novel 5-sulfo-substituted fiber-reactive 2-amino-naphthalene, and fibre-reactive azo dyes thereof | HOECHST CELANESE CORPORATION (US) | 1989-12-06 | — | — | EP | disclosed |