Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5033087 | 0.80 | PBRM1 (0.52) | PBRM1LMNATDP1NPC1MITF | |
| SCHEMBL10005649 | 0.80 | NR4A2 (0.62) | PBRM1LMNANPC1MITFPOLB | |
| SCHEMBL946292 | 0.79 | TDP1 (0.67) | L3MBTL1LMNATDP1MAPTNPC1 | |
| SCHEMBL13483577 | 0.78 | IDO1 (0.40) | L3MBTL1LMNATDP1MAPTNPC1 | |
| SCHEMBL9504899 | 0.76 | PBRM1 (0.45) | PBRM1LMNANPC1MITFPOLB | |
| SCHEMBL655728 | 0.76 | PBRM1 (0.52) | PBRM1L3MBTL1LMNAMAPTNPC1 | |
| SCHEMBL1538686 | 0.76 | PBRM1 (0.52) | PBRM1L3MBTL1LMNATDP1MAPT | |
| SCHEMBL27324757 | 0.76 | PBRM1 (0.52) | PBRM1L3MBTL1LMNATDP1MAPT | |
| SCHEMBL28359889 | 0.75 | PBRM1 (0.59) | PBRM1LMNATDP1MAPTNPC1 | |
| SCHEMBL19287159 | 0.74 | HDAC1 (0.60) | LMNATDP1MAPTNPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395991-B1 | 3-AMINOPHENYL-1,5-PENTANEDIONES | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | claimed |
| US-5053524-A | Intermediate for synthesis of triphenylcyclopentadiene dyes | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | claimed |
| EP-0395991-A1 | 3-Aminophenyl-1,5-pentanediones | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | claimed |
| EP-0395991-B1 | 3-AMINOPHENYL-1,5-PENTANEDIONES | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | disclosed |
| EP-0395991-B1 | 3-AMINOPHENYL-1,5-PENTANEDIONES | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | disclosed |
| US-5053524-A | Intermediate for synthesis of triphenylcyclopentadiene dyes | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| US-5053524-A | Intermediate for synthesis of triphenylcyclopentadiene dyes | BASF AKTIENGESELLSCHAFT (DE) | 1991-10-01 | — | — | US | disclosed |
| EP-0395991-A1 | 3-Aminophenyl-1,5-pentanediones | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0395991-A1 | 3-Aminophenyl-1,5-pentanediones | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |
| EP-0395991-A1 | 3-Aminophenyl-1,5-pentanediones | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |