Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503703 | 0.76 | PBRM1 (0.46) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL13622519 | 0.76 | F2 (0.53) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL1538686 | 0.75 | PBRM1 (0.52) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL27324757 | 0.75 | PBRM1 (0.52) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL10005649 | 0.75 | NR4A2 (0.62) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL655728 | 0.75 | PBRM1 (0.52) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL28359889 | 0.74 | PBRM1 (0.59) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL633209 | 0.72 | PBRM1 (0.57) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL3373649 | 0.72 | PBRM1 (0.57) | PBRM1NPC1MITFLMNAPOLB | |
| SCHEMBL5033087 | 0.71 | PBRM1 (0.52) | PBRM1NPC1MITFLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0395991-B1 | 3-AMINOPHENYL-1,5-PENTANEDIONES | BASF Aktiengesellschaft (DE) | 1993-06-23 | — | — | EP | disclosed |
| EP-0395991-A1 | 3-Aminophenyl-1,5-pentanediones | BASF Aktiengesellschaft (DE) | 1990-11-07 | — | — | EP | disclosed |