Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.48 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355608 | 0.80 | PTGS2 (0.49) | NPSR1ALDH1A1PTGS2PTGS1HPGD | |
| SCHEMBL6375687 | 0.80 | MAPT (0.96) | MAPTHTTNPSR1ALDH1A1CYP2C9 | |
| SCHEMBL4007061 | 0.78 | MEN1 (0.54) | MAPTNPSR1PTGS2PTGS1HPGD | |
| SCHEMBL11576626 | 0.77 | MAPT (0.78) | MAPTHTTNPSR1ALDH1A1CYP2C9 | |
| SCHEMBL31409467 | 0.77 | CYP2C19 (0.54) | NPSR1ALDH1A1CYP2C9PTGS2PTGS1 | |
| SCHEMBL5022505 | 0.77 | CYP2C19 (0.54) | NPSR1ALDH1A1CYP2C9PTGS2PTGS1 | |
| SCHEMBL31083332 | 0.77 | CYP2C19 (0.54) | NPSR1ALDH1A1CYP2C9PTGS2PTGS1 | |
| SCHEMBL31409463 | 0.77 | CYP2C19 (0.54) | NPSR1ALDH1A1CYP2C9PTGS2PTGS1 | |
| SCHEMBL12824490 | 0.75 | PTGS2 (0.45) | MAPTHTTNPSR1ALDH1A1NPC1 | |
| SCHEMBL28139091 | 0.75 | MAPT (0.73) | MAPTHTTNPSR1ALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0331073-B1 | BENZHYDRYLAMINE DERIVATIVES | Chugai Seiyaku Kabushiki Kaisha (JP) | 1993-07-28 | — | — | EP | disclosed |
| US-5051526-A | Reagents for solid phase synthesis of polypeptides | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-09-24 | — | — | US | disclosed |
| US-4965405-A | INTERMEDIATE FOR POLYPEPTIDE SYNTHESIS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1990-10-23 | — | — | US | disclosed |
| EP-0331073-A2 | Benzhydrylamine derivatives | Chugai Seiyaku Kabushiki Kaisha (JP) | 1989-09-06 | — | — | EP | disclosed |