Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | CDC42 | P60953 | 1/20 | 0.42 |
| ▸ | RAC1 | P63000 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5022505 | 0.83 | CYP2C19 (0.54) | PTGS2PTGS1MT-CO2ALDH1A1HPGD | |
| SCHEMBL31409467 | 0.83 | CYP2C19 (0.54) | PTGS2PTGS1MT-CO2ALDH1A1HPGD | |
| SCHEMBL31409463 | 0.83 | CYP2C19 (0.54) | PTGS2PTGS1MT-CO2ALDH1A1HPGD | |
| SCHEMBL487560 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDNPSR1LCK | |
| SCHEMBL31083332 | 0.83 | CYP2C19 (0.54) | PTGS2PTGS1MT-CO2ALDH1A1HPGD | |
| SCHEMBL2742620 | 0.83 | ALDH1A1 (0.51) | PTGS2PTGS1MT-CO2KDM4EALDH1A1 | |
| SCHEMBL11089399 | 0.81 | PTGS2 (0.49) | PTGS2PTGS1MT-CO2KDM4EALDH1A1 | |
| SCHEMBL9503753 | 0.80 | MAPT (0.62) | PTGS2PTGS1ALDH1A1HPGDNPSR1 | |
| SCHEMBL7241661 | 0.79 | ALDH1A1 (0.51) | PTGS2PTGS1MT-CO2ALDH1A1MEN1 | |
| SCHEMBL19374620 | 0.78 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDNPSR1LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176204-B2 | Substituted carboxylic acid derivatives | KYORIN PAHRMACEUTICAL CO., LTD. (JP) | 2007-02-13 | — | — | US | disclosed |
| US-20050101521-A1 | Substituted carboxylic acid derivatives | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | US | disclosed |
| EP-1348698-A1 | SUBSTITUTED CARBOXYLIC ACID DERIVATIVES | Kyorin Pharmaceutical Co., Ltd. (JP) | 2003-10-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050101521-A1 | Substituted carboxylic acid derivatives | PPARG, PPARA, PPARD | PTGS2 2204/4885PTGS1 1350/4885MT-CO2 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.