Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11474768 | 0.85 | KDM4E (0.55) | KDM4EALDH1A1MAPTTDP1TP53 | |
| SCHEMBL10652417 | 0.83 | ALDH1A1 (0.40) | KDM4EALDH1A1MAPTTDP1HPGD | |
| SCHEMBL3782017 | 0.76 | PTPRF (0.46) | KDM4EALDH1A1MAPTTDP1TP53 | |
| SCHEMBL3788674 | 0.72 | SIRT1 (0.47) | KDM4EALDH1A1TDP1TP53SMN1; SMN2 | |
| SCHEMBL8496004 | 0.70 | CDK1 (0.54) | KDM4EALDH1A1MAPTTDP1TP53 | |
| SCHEMBL27596875 | 0.69 | MAPT (0.41) | KDM4EALDH1A1MAPTTDP1TP53 | |
| SCHEMBL30408659 | 0.67 | POLB (0.45) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL13302911 | 0.67 | POLB (0.45) | KDM4EALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL26124118 | 0.67 | KDM4E (0.34) | KDM4EALDH1A1MAPTTDP1TP53 | |
| SCHEMBL675985 | 0.66 | KDM4E (0.62) | KDM4EALDH1A1MAPTTDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0377406-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5013707-A | Pressure- or heat-sensitive recording material | CIBA-GEIGY CORPORATION (US) | 1991-05-07 | — | — | US | disclosed |
| EP-0377406-A1 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-07-11 | — | — | EP | disclosed |