Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.54 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | PTAFR | P25105 | 1/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497298 | 0.88 | CDK1 (0.53) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL3788674 | 0.86 | SIRT1 (0.47) | ACHEGAARAB9AALDH1A1KDM4E | |
| SCHEMBL27596875 | 0.77 | MAPT (0.41) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL3782017 | 0.75 | PTPRF (0.46) | ACHERAB9AALDH1A1KDM4ETP53 | |
| SCHEMBL11474768 | 0.75 | KDM4E (0.55) | ACHERAB9AALDH1A1KDM4ETP53 | |
| SCHEMBL8631707 | 0.71 | ACHE (0.58) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL10693011 | 0.71 | CDK1 (0.50) | CDK1CCNB1GSK3AGSK3BCDK5 | |
| SCHEMBL9503807 | 0.70 | KDM4E (0.50) | ACHEMAPK1RAB9AALDH1A1KDM4E | |
| SCHEMBL16108413 | 0.70 | ALDH1A1 (0.44) | GAANPSR1ALDH1A1KDM4EMAPT | |
| SCHEMBL8064381 | 0.69 | CDK1 (0.45) | CDK1CCNB1GSK3AGSK3BCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0701991-B1 | Process for the preparation of lignin analogues and starting materials therefor | SHIONOGI & CO (JP) | 1999-01-20 | — | — | EP | disclosed |