Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.59 |
| ▸ | CASP6 | P55212 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | MMP13 | P45452 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.53 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8784484 | 0.98 | SNCA (0.58) | SNCACASP6CA2CA1CA12 | |
| Water SCHEMBL11035834 | 0.98 | SNCA (0.58) | SNCACASP6CA2CA1CA12 | |
| SCHEMBL6079123 | 0.95 | CASP6 (0.56) | SNCACASP6CA2CA1CA12 | |
| SCHEMBL6079107 | 0.93 | CASP6 (0.55) | SNCACASP6CA2CA1CA12 | |
| Pyridine SCHEMBL950273 | 0.89 | SNCA (0.54) | SNCACASP6CA2CA1CA12 | |
| SCHEMBL10388565 | 0.85 | CYP2C19 (0.48) | SNCACASP6CA2CA1CA12 | |
| SCHEMBL8577441 | 0.85 | MEN1 (0.68) | CA2CA1CA12CA9KDM4E | |
| SCHEMBL949134 | 0.85 | CA2 (0.53) | CA2CA1CA12CA9MMP1 | |
| SCHEMBL8784476 | 0.85 | CA2 (0.53) | CA2CA1CA12CA9MMP1 | |
| SCHEMBL1803097 | 0.85 | NT5E (0.75) | SNCACASP6CA2CA1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4908478-A | Single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | claimed |
| EP-0218005-B1 | SINGLE POT PROCESS FOR THE PRODUCTION OF 2-ACETAMIDONAPHTHALENE-6-SULPHONIC ACID WITH A HIGH PURITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-23 | — | — | EP | claimed |
| US-8419849-B2 | Disazo dyes and their use in ink-jet printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2013-04-16 | — | — | US | disclosed |
| EP-2344589-B1 | DISAZO COMPOUNDS AND THEIR USE IN INK-JET PRINTING | FUJIFILM IMAGING COLORANTS LTD (GB) | 2013-01-16 | — | — | EP | disclosed |
| US-20110195236-A1 | Disazo Dyes And Their Use in Ink-Jet Printing | FUJIFILM CORPORATION (JP) | 2011-08-11 | — | — | US | disclosed |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| WO-2010041066-A2 | DISAZO COMPOUNDS AND THEIR USE IN INK-JET PRINTING | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2010-04-15 | — | — | WO | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| EP-1564213-A1 | IMIDAZOLE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE | Takeda Pharmaceutical Company Limited (JP) | 2005-08-17 | — | — | EP | disclosed |
| US-4960870-A | DYEING WOOL, POLYAMIDES; FIBER REACTIVE DYES | CIBA-GEIGY CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |
| US-4908478-A | Single-vessel process for preparing 2-acetaminonaphthalene-6-sulfonic acid of high purity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-03-13 | — | — | US | disclosed |
| EP-0210492-B1 | WATER-SOLUBLE MONOAZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS | HOECHST CELANESE CORPORATION (US) | 1989-03-08 | — | — | EP | disclosed |
| EP-0218005-B1 | SINGLE POT PROCESS FOR THE PRODUCTION OF 2-ACETAMIDONAPHTHALENE-6-SULPHONIC ACID WITH A HIGH PURITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-23 | — | — | EP | disclosed |
| EP-0218005-B1 | SINGLE POT PROCESS FOR THE PRODUCTION OF 2-ACETAMIDONAPHTHALENE-6-SULPHONIC ACID WITH A HIGH PURITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4749523-A | NEUTRALIZING ACID AND SUBSEQUENT AMINE ACYLATION TO AMIDE GROUP; EFFICIENT | HOECHST CELANESE CORPORATION (US) | 1988-06-07 | — | — | US | disclosed |
| EP-0168680-B1 | SOLID PHASE ACYLATION OF AMINOSULFONIC ACIDS | HOECHST CELANESE CORPORATION (US) | 1988-03-09 | — | — | EP | disclosed |
| EP-0218005-A1 | Single pot process for the production of 2-acetamidonaphthalene-6-sulphonic acid with a high purity | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0218005-A1 | Single pot process for the production of 2-acetamidonaphthalene-6-sulphonic acid with a high purity | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-04-15 | — | — | EP | disclosed |
| EP-0168680-A1 | Solid phase acylation of aminosulfonic acids | HOECHST CELANESE CORPORATION (US) | 1986-01-22 | — | — | EP | disclosed |
| US-4487725-A | Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | SNCA 3053/4885CASP6 3275/4885CA2 2796/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | SNCA 3232/4885CASP6 3326/4885CA2 3237/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.