SCHEMBL9504026

SCHEMBL9504026

CC(C)c1cccc(C(C)C)c1NC(=O)NC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SOAT2 O75908 1/20 0.57
SOAT1 P35610 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9848388 0.85
SCHEMBL9195227 0.83 HTT (0.54)
SCHEMBL6335727 0.82 SOAT2 (0.57) SOAT2SOAT1
SCHEMBL6335726 0.82 SOAT2 (0.57) SOAT2SOAT1
SCHEMBL9504118 0.80 LMNA (0.58)
SCHEMBL9848382 0.80
SCHEMBL9848512 0.80
SCHEMBL9848470 0.78
SCHEMBL9848403 0.78
SCHEMBL9848439 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0335374-B1 N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents WARNER-LAMBERT COMPANY (US) 1993-06-30 EP claimed
US-5116848-A N-(((2,6-DISUBSTITUTED)PHENYL)-N-DIARYLALKYL)UREAS AS ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS WARNER-LAMBERT COMPANY (US) 1992-05-26 US claimed
EP-0335374-B1 N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents WARNER-LAMBERT COMPANY (US) 1993-06-30 EP disclosed
US-5116848-A N-(((2,6-DISUBSTITUTED)PHENYL)-N-DIARYLALKYL)UREAS AS ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS WARNER-LAMBERT COMPANY (US) 1992-05-26 US disclosed
EP-0335374-A2 N-[[(2,6-disubstituted)phenyl]-N'-diarylalkyl] ureas as antihyperlipidemic and antiatherosclerotic agents WARNER-LAMBERT COMPANY (US) 1989-10-04 EP disclosed