Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | CYSLTR1 | Q9Y271 | 9/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.54 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.54 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9593916 | 0.90 | ALOX5 (0.59) | ALOX5CYSLTR1FFAR1AKR1B1CYSLTR2 | |
| SCHEMBL9380104 | 0.84 | ALOX5 (0.58) | ALOX5 | |
| SCHEMBL9505352 | 0.80 | ALOX5 (0.85) | ALOX5CYSLTR1FFAR1AKR1B1GPBAR1 | |
| SCHEMBL7807149 | 0.79 | FFAR1 (0.68) | ALOX5CYSLTR1FFAR1AKR1B1CYSLTR2 | |
| SCHEMBL9505341 | 0.79 | ALOX5 (0.62) | ALOX5CYSLTR1FFAR1AKR1B1 | |
| SCHEMBL9590051 | 0.79 | ALOX5 (0.58) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7801881 | 0.79 | CYSLTR1 (0.64) | ALOX5CYSLTR1FFAR1AKR1B1CYSLTR2 | |
| SCHEMBL10512475 | 0.77 | PDE10A (0.77) | CYSLTR1CYSLTR2GPBAR1PDE10A | |
| SCHEMBL9504039 | 0.77 | ALOX5 (0.60) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL10692251 | 0.77 | ALOX5 (0.76) | ALOX5CYSLTR1FFAR1AKR1B1CYSLTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |