Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.76 |
| ▸ | CYSLTR1 | Q9Y271 | 10/20 | 0.63 |
| ▸ | CYSLTR2 | Q9NS75 | 8/20 | 0.63 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.55 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.55 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692276 | 0.86 | ALOX5 (1.00) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9053241 | 0.84 | CYSLTR1 (0.73) | ALOX5CYSLTR1CYSLTR2GPBAR1FFAR1 | |
| SCHEMBL9656045 | 0.80 | CYSLTR1 (0.85) | ALOX5CYSLTR1CYSLTR2GPBAR1FFAR1 | |
| SCHEMBL10696181 | 0.79 | ALOX5 (0.69) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9053379 | 0.79 | ALOX5 (0.72) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL7458734 | 0.79 | CYSLTR1 (0.68) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL9505352 | 0.78 | ALOX5 (0.85) | ALOX5CYSLTR1GPBAR1FFAR1AKR1B1 | |
| SCHEMBL7716691 | 0.78 | CYSLTR1 (0.88) | ALOX5CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL14021559 | 0.78 | CYSLTR1 (1.00) | ALOX5CYSLTR1CYSLTR2GPBAR1FFAR1 | |
| SCHEMBL9022221 | 0.78 | CYSLTR1 (0.67) | ALOX5CYSLTR1CYSLTR2GPBAR1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | claimed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | claimed |
| US-4792560-A | ANTIALLERGENS; ANTIINFLAMMATORY AGENTS | RORER PHARMACEUTICAL CORPORATION (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0196674-A2 | Hydroxamates as modulators of arachidonic acid metabolic pathways | USV PHARMACEUTICAL CORPORATION (US) | 1986-10-08 | — | — | EP | disclosed |