Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505234 | 0.72 | GAA (0.61) | KDM4EALDH1A1TSHRGAAHPGD | |
| SCHEMBL9513394 | 0.70 | ABCC1 (0.58) | KDM4EALDH1A1TSHRSMN1; SMN2ABCC1 | |
| SCHEMBL9511512 | 0.69 | CACNA1F (0.61) | KDM4EALDH1A1TSHRSMN1; SMN2ABCC1 | |
| SCHEMBL5456439 | 0.68 | KDM4E (0.50) | KDM4EALDH1A1TSHRSMN1; SMN2ABCC1 | |
| SCHEMBL6590571 | 0.66 | CACNA1F (0.82) | TSHRLMNACACNA1FCACNA1DCACNA1S | |
| SCHEMBL9513433 | 0.66 | CACNA1F (0.68) | KDM4EALDH1A1TSHRGAAHPGD | |
| SCHEMBL9505389 | 0.66 | CACNA1F (0.68) | KDM4EALDH1A1TSHRGAAHPGD | |
| SCHEMBL9732316 | 0.66 | CACNA1F (0.55) | KDM4EALDH1A1TSHRSMN1; SMN2ABCC1 | |
| SCHEMBL7817206 | 0.65 | KDM4E (0.88) | KDM4EALDH1A1TSHRSMN1; SMN2ABCC1 | |
| SCHEMBL7237214 | 0.64 | ADORA3 (0.82) | KDM4EALDH1A1TSHRSMN1; SMN2ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| WO-1990009376-A1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-23 | — | — | WO | disclosed |