SCHEMBL9504258

SCHEMBL9504258

C#CC[Si](CCCC)(CCCC)CCCC

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.31
HTT P42858 3/20 0.31
LMNA P02545 3/20 0.31
RAB9A P51151 2/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20658171 0.90 TSHR (0.38) SMN1; SMN2HTTLMNARAB9AMEN1
SCHEMBL20658194 0.78 TSHR (0.33) LMNATSHR
SCHEMBL2761275 0.77 SMN1; SMN2 (0.30) SMN1; SMN2HTTLMNARAB9AMEN1
SCHEMBL434505 0.73 TSHR (0.46) SMN1; SMN2LMNAMEN1KMT2ATSHR
SCHEMBL4325547 0.71
SCHEMBL10764344 0.70
SCHEMBL10401632 0.70 TSHR (0.43) SMN1; SMN2LMNAMEN1KMT2ATSHR
SCHEMBL10401717 0.70 TSHR (0.43) SMN1; SMN2LMNAMEN1KMT2ATSHR
SCHEMBL6545021 0.69 ALDH1A1 (0.33)
SCHEMBL20658201 0.68 TSHR (0.42) LMNAMEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10711075-B2 Method of preparing rubber composition including syndiotactic 1,2-polybutadiene KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2020-07-14 US disclosed
US-20190023815-A1 METHOD OF PREPARING RUBBER COMPOSITION INCLUDING SYNDIOTACTIC 1,2-POLYBUTADIENE KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2019-01-24 US disclosed
EP-0339516-B1 CATALYST AND PROCESS FOR THE PREPARATION OF POLYMERS OF TRI-SUBSTITUTED SILYLALKYNES AIR PRODUCTS AND CHEMICALS, INC. (US) 1993-06-09 EP disclosed
US-4902763-A USING GROUP V OR VI METAL HALIDE CATALYST AND TRIALKYLGERMYALKYNE COMPOUND PROMOTER AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-02-20 US disclosed
EP-0343556-A2 Process for the polymerization of tri-substituted silylalkynes AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-11-29 EP disclosed
EP-0339516-A2 Catalyst and process for the preparation of polymers of tri-substituted silylalkynes AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-11-02 EP disclosed
US-4835229-A METAL HALIDE, TERTIARY AMINE AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-05-30 US disclosed