Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 4/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504272 | 0.81 | ALOX5AP (0.60) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL9503948 | 0.81 | ALOX5 (0.53) | ALOX5APALOX5 | |
| SCHEMBL9335358 | 0.80 | GPBAR1 (0.60) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL9584531 | 0.78 | ALOX5 (0.61) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL7593162 | 0.75 | GPBAR1 (0.67) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL10512475 | 0.75 | PDE10A (0.77) | CYSLTR1GPBAR1PDE10ACYSLTR2 | |
| SCHEMBL3534448 | 0.75 | GPBAR1 (0.74) | CYSLTR1GPBAR1PDE10AALOX5CYSLTR2 | |
| SCHEMBL7595304 | 0.75 | CYSLTR1 (0.66) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL9460524 | 0.75 | CYSLTR1 (0.66) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 | |
| SCHEMBL7599114 | 0.74 | GPBAR1 (0.65) | ALOX5APCYSLTR1GPBAR1PDE10AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250693-A | Lipoxygenase inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-05 | — | — | US | claimed |
| EP-0547148-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-06-23 | — | — | EP | claimed |
| WO-1992004325-A1 | NAPHTHALENEPROPIONIC ACID DERIVATIVES AS ANTI-INFLAMMATORY/ANTIALLERGIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-03-19 | — | — | WO | claimed |