Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9144287 | 0.84 | KIF11 (0.31) | KIF11 | |
| SCHEMBL4634586 | 0.81 | KIF11 (0.31) | KIF11 | |
| SCHEMBL25991368 | 0.77 | CA1 (0.32) | CA12CA1CA2CA7CA13 | |
| SCHEMBL9507060 | 0.77 | CA1 (0.32) | CA12CA1CA2CA7CA13 | |
| SCHEMBL9342462 | 0.76 | CA1 (0.35) | CA12CA1CA2CA7CA13 | |
| SCHEMBL27264874 | 0.76 | DAO (0.32) | — | |
| SCHEMBL461597 | 0.76 | CA1 (0.43) | CA12CA1CA2CA7CA13 | |
| SCHEMBL9142584 | 0.74 | ALDH1A1 (0.32) | KIF11 | |
| SCHEMBL29031994 | 0.74 | CA1 (0.33) | CA12CA1CA2CA7CA13 | |
| SCHEMBL29031993 | 0.74 | CA1 (0.33) | CA12CA1CA2CA7CA13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0315863-B1 | Trifluoromethylamino benzenes containing fluorine, and their preparation | BAYER AG (DE) | 1993-11-18 | — | — | EP | disclosed |
| EP-0318796-B1 | SUBSTITUTED BENZOYL(THIO) UREAS | BAYER AG (DE) | 1993-06-16 | — | — | EP | disclosed |
| US-5096928-A | Caterpillars | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | disclosed |
| US-5082971-A | TRIFLUOROMETHYLAMINOBENZENES CONTAINING FLUORINE AND/OR CHLORINE AND THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-21 | — | — | US | disclosed |
| EP-0318796-A2 | Substituted benzoyl(thio) ureas | BAYER AG (DE) | 1989-06-07 | — | — | EP | disclosed |