SCHEMBL9504530

SCHEMBL9504530

CC(C)(Cl)CN1CCOCC1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.39
ALDH1A1 P00352 3/20 0.39
RECQL P46063 1/20 0.39
USP2 O75604 1/20 0.38
HRH3 Q9Y5N1 1/20 0.38
LMNA P02545 1/20 0.37
KDM4E B2RXH2 4/20 0.37
KEAP1 Q14145 1/20 0.37
GAA P10253 1/20 0.36
SIGMAR1 Q99720 2/20 0.36
HSD17B10 Q99714 2/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
ALOX15 P16050 1/20 0.34
TSHR P16473 1/20 0.34
CYP2A13 Q16696 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL179555 0.80 ALDH1A1 (0.41) SMN1; SMN2ALDH1A1RECQLUSP2HRH3
SCHEMBL10153213 0.78 ALDH1A1 (0.40) SMN1; SMN2ALDH1A1RECQLUSP2HRH3
SCHEMBL11483109 0.77 SMN1; SMN2 (0.37) SMN1; SMN2ALDH1A1RECQLUSP2HRH3
SCHEMBL1430804 0.76 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1RECQLUSP2LMNA
SCHEMBL20623013 0.76 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1RECQLUSP2LMNA
SCHEMBL862113 0.76 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1RECQLUSP2KDM4E
SCHEMBL1708968 0.76 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1RECQLUSP2LMNA
SCHEMBL6484208 0.76 ALDH1A1 (0.52) SMN1; SMN2ALDH1A1RECQLUSP2LMNA
SCHEMBL17310700 0.76 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1RECQLUSP2LMNA
SCHEMBL17392772 0.76 SMN1; SMN2 (0.43) SMN1; SMN2ALDH1A1RECQLUSP2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426987-B1 RAPIDLY IMMOBILIZING PAPER COATING COMPOSITIONS National Starch and Chemical Investment Holding Corporation (US) 1993-07-14 EP claimed
US-5093159-A Cationic Starch, Pigment, Base NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1992-03-03 US claimed
EP-0426987-A1 Rapidly immobilizing paper coating compositions National Starch and Chemical Investment Holding Corporation (US) 1991-05-15 EP claimed
EP-0426987-B1 RAPIDLY IMMOBILIZING PAPER COATING COMPOSITIONS National Starch and Chemical Investment Holding Corporation (US) 1993-07-14 EP disclosed
US-5093159-A Cationic Starch, Pigment, Base NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1992-03-03 US disclosed
EP-0426987-A1 Rapidly immobilizing paper coating compositions National Starch and Chemical Investment Holding Corporation (US) 1991-05-15 EP disclosed
US-4230850-A HYPOTENSIVE AGENTS, VASODILATION LIPHA, LYONNAISE INDUSTRIELLE PHARMACEUTIQUE (FR) 1980-10-28 US disclosed