Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25913211 | 0.86 | GPR84 (0.39) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL9108868 | 0.84 | ACHE (0.36) | USP2ALOX15PTGS2MAPTCYP1A2 | |
| SCHEMBL31375356 | 0.76 | TYR (0.58) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL31375351 | 0.76 | TYR (0.58) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL28298713 | 0.76 | TYR (0.58) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL48994 | 0.76 | TYR (0.58) | TYRUSP2GAAALOX15RAD51 | |
| Bromide SCHEMBL29769307 | 0.74 | TYR (0.56) | TYRUSP2GAAALOX15RAD51 | |
| Hydrochloric Acid SCHEMBL4625112 | 0.74 | TYR (0.56) | TYRUSP2GAAALOX15RAD51 | |
| Bromide SCHEMBL27546379 | 0.74 | TYR (0.56) | TYRUSP2GAAALOX15RAD51 | |
| SCHEMBL9506012 | 0.71 | MAPT (0.34) | TYRUSP2GAAALOX15RAD51 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335477-B1 | THE USE OF N-SUBSTITUTED-5,6-DIHYDROXYINDOLES AS A HAIR COLORING AGENT | Bristol-Myers Squibb Company (US) | 1993-07-21 | — | — | EP | claimed |