Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813056 | 0.81 | — | — | |
| SCHEMBL15188666 | 0.81 | SMN1; SMN2 (0.39) | TSHRTP53ALDH1A1LMNAKMT2A | |
| SCHEMBL8367939 | 0.77 | TSHR (0.44) | TSHRTP53ALDH1A1LMNATHRB | |
| SCHEMBL21978534 | 0.76 | TSHR (0.32) | TSHRTP53 | |
| SCHEMBL722795 | 0.74 | OR51E2 (0.42) | TSHRLMNAOR51E2CYP2C9 | |
| SCHEMBL19821760 | 0.74 | — | — | |
| SCHEMBL16745705 | 0.73 | TP53 (0.39) | TP53 | |
| SCHEMBL15690557 | 0.72 | — | — | |
| SCHEMBL10353512 | 0.72 | TSHR (0.39) | TSHRTP53ALDH1A1LMNATHRB | |
| SCHEMBL1299349 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082735-B1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | PROCTER & GAMBLE (US) | 2018-05-02 | — | — | EP | claimed |
| EP-3082735-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | The Procter & Gamble Company (US) | 2016-10-26 | — | — | EP | claimed |
| EP-3082750-A1 | SHAPING KERATIN FIBRES USING A REDUCING COMPOSITION AND A FIXING COMPOSITION | The Procter & Gamble Company (US) | 2016-10-26 | — | — | EP | claimed |
| WO-2015094838-A1 | SHAPING KERATIN FIBRES USING A REDUCING COMPOSITION AND A FIXING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| WO-2015095671-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | claimed |
| US-20150174023-A1 | SHAPING KERATIN FIBRES USING A REDUCING COMPOSITION AND A FIXING COMPOSITION | THE PROCTER & GAMBLE COMPANY | 2015-06-25 | — | — | US | claimed |
| US-20150174030-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY | 2015-06-25 | — | — | US | claimed |
| US-11129784-B2 | Shaping keratin fibres using oxoethanoic acid and/or derivatives thereof | THE PROCTER AND GAMBLE COMPANY (US) | 2021-09-28 | — | — | US | disclosed |
| US-11129784-B2 | Shaping keratin fibres using oxoethanoic acid and/or derivatives thereof | THE PROCTER AND GAMBLE COMPANY (US) | 2021-09-28 | — | — | US | disclosed |
| US-10945931-B2 | Shaping keratin fibres using dialdehyde compounds | THE PROCTER AND GAMBLE COMPANY (US) | 2021-03-16 | — | — | US | disclosed |
| US-10912726-B2 | Shaping keratin fibres using a reducing composition and a fixing composition | THE PROCTER AND GAMBLE COMPANY (US) | 2021-02-09 | — | — | US | disclosed |
| US-10568826-B2 | Shaping keratin fibres using a pretreatment and a protein crosslinking composition | THE PROCTER AND GAMBLE COMPANY (US) | 2020-02-25 | — | — | US | disclosed |
| US-10449136-B2 | Hair shaping composition | CONOPCO, INC. (US) | 2019-10-22 | — | — | US | disclosed |
| WO-2015094838-A1 | SHAPING KERATIN FIBRES USING A REDUCING COMPOSITION AND A FIXING COMPOSITION | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015095671-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015095671-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | THE PROCTER & GAMBLE COMPANY (US) | 2015-06-25 | — | — | WO | disclosed |
| EP-0408644-B1 | PROCESS FOR PREPARATION OF AN OXYACETIC ACID/HYDROXYETHYL ETHER COMPOUND | EASTMAN KODAK COMPANY (US) | 1993-07-28 | — | — | EP | disclosed |
| EP-0408644-A1 | PROCESS FOR PREPARATION OF AN OXYACETIC ACID/HYDROXYETHYL ETHER COMPOUND. | EASTMAN KODAK CO (US) | 1991-01-23 | — | — | EP | disclosed |
| WO-1989009761-A1 | PROCESS FOR PREPARATION OF AN OXYACETIC ACID/HYDROXYETHYL ETHER COMPOUND | EASTMAN KODAK COMPANY (US) | 1989-10-19 | — | — | WO | disclosed |
| US-4791224-A | Process for preparation of an oxyacetic acid/hydroxyethyl ether compound | EASTMAN KODAK COMPANY (US) | 1988-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10449136-B2 | Hair shaping composition | DPM1, GLA, CYP24A1 | TSHR 4632/4885TP53 1648/4885ALDH1A1 807/4885 |
| US-20150174023-A1 | SHAPING KERATIN FIBRES USING A REDUCING COMPOSITION AND A FIXING COMPOSITION | KRT18, SMCHD1, KDM7A | TSHR 4575/4885TP53 3330/4885ALDH1A1 2682/4885 |
| US-10568826-B2 | Shaping keratin fibres using a pretreatment and a protein crosslinking composition | KRT18, COL14A1, COL2A1 | TSHR 4537/4885TP53 2144/4885ALDH1A1 3266/4885 |
| US-11129784-B2 | Shaping keratin fibres using oxoethanoic acid and/or derivatives thereof | KRT18, KDM7A, FTO | TSHR 4173/4885TP53 2610/4885ALDH1A1 707/4885 |
| US-10912726-B2 | Shaping keratin fibres using a reducing composition and a fixing composition | KRT18, SMCHD1, KDM7A | TSHR 4575/4885TP53 3330/4885ALDH1A1 2682/4885 |
| US-10945931-B2 | Shaping keratin fibres using dialdehyde compounds | KRT18, DSP, COL14A1 | TSHR 4396/4885TP53 1530/4885ALDH1A1 406/4885 |
| US-20150174030-A1 | SHAPING KERATIN FIBRES USING OXOETHANOIC ACID AND/OR DERIVATIVES THEREOF | KRT18, KDM7A, FTO | TSHR 4173/4885TP53 2610/4885ALDH1A1 707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.