Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | IL2 | P60568 | 2/20 | 0.44 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9505640 | 0.90 | TRPV1 (0.50) | MEN1KMT2AMAPTNTRK1CDK19 | |
| SCHEMBL9504693 | 0.87 | IL2 (0.52) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9506643 | 0.87 | RXFP1 (0.49) | MEN1KMT2AMAPTNTRK1CDK19 | |
| SCHEMBL352658 | 0.83 | MEN1 (0.54) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL29608194 | 0.83 | MEN1 (0.54) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8660904 | 0.81 | KMT2A (0.64) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL11339685 | 0.78 | TLR7 (0.57) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL9503789 | 0.77 | TRPV1 (0.49) | MEN1KMT2AMAPTIL2TLR7 | |
| SCHEMBL10606310 | 0.76 | MEN1 (0.52) | MEN1KMT2AMAPTUSP2ALOX15 | |
| Flufenoxuron SCHEMBL8407576 | 0.75 | MEN1 (0.52) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0318882-B1 | (THIO)BENZOYL UREAS, FUNCTIONAL DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS AND PESTICIDAL USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-06-23 | — | — | EP | claimed |