Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9112610 | 0.89 | ALDH1A1 (0.51) | ALDH1A1GPR35SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL9506799 | 0.85 | SRC (0.35) | ALDH1A1GPR35SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL9508601 | 0.72 | SRC (0.42) | ALDH1A1GPR35SMN1; SMN2HPGDMAPK1 | |
| SCHEMBL9506012 | 0.69 | MAPT (0.34) | GAAMAPTALOX15 | |
| SCHEMBL29904251 | 0.67 | MAPT (0.54) | ALDH1A1HPGDHTTTDP1KDM4E | |
| SCHEMBL30011 | 0.67 | MAPT (0.54) | ALDH1A1HPGDHTTTDP1KDM4E | |
| SCHEMBL28686 | 0.67 | MAPT (0.54) | ALDH1A1TSHRGAACA12CA1 | |
| SCHEMBL30597526 | 0.67 | MAPT (0.54) | ALDH1A1TSHRGAACA12CA1 | |
| SCHEMBL31375351 | 0.66 | TYR (0.58) | ALDH1A1HPGDMAPK1GAAMEN1 | |
| SCHEMBL31375356 | 0.66 | TYR (0.58) | ALDH1A1HPGDMAPK1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335477-B1 | THE USE OF N-SUBSTITUTED-5,6-DIHYDROXYINDOLES AS A HAIR COLORING AGENT | Bristol-Myers Squibb Company (US) | 1993-07-21 | — | — | EP | claimed |