Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.42 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | PRKACG | P22612 | 1/20 | 0.42 |
| ▸ | PRKACB | P22694 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9506799 | 0.88 | SRC (0.35) | SRCNOX4PRKACAPRKACGPRKACB | |
| SCHEMBL257518 | 0.83 | SLC6A2 (0.49) | CDC7MAPTALDH1A1HTT | |
| SCHEMBL9112610 | 0.81 | ALDH1A1 (0.51) | NOX4CDC7MAPTGAAGPR35 | |
| SCHEMBL6298958 | 0.78 | ACHE (0.49) | MAPTGAAALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5659157 | 0.78 | BIRC5 (0.47) | CDC7MAPTALDH1A1TP53SMN1; SMN2 | |
| SCHEMBL5659240 | 0.76 | BIRC5 (0.57) | PRKACAPRKACGPRKACBMAPTALDH1A1 | |
| SCHEMBL9508652 | 0.76 | PRKCI (0.38) | SRCCDC7MAPTGPR35ALDH1A1 | |
| SCHEMBL5109303 | 0.75 | GAA (0.46) | MAPTGAAALDH1A1 | |
| SCHEMBL16862099 | 0.75 | KCNH2 (0.54) | CDC7MAPTALDH1A1MAPK1 | |
| SCHEMBL6297057 | 0.74 | MEN1 (0.46) | MAPTALDH1A1HPGDMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335477-B1 | THE USE OF N-SUBSTITUTED-5,6-DIHYDROXYINDOLES AS A HAIR COLORING AGENT | Bristol-Myers Squibb Company (US) | 1993-07-21 | — | — | EP | claimed |
| EP-0335477-A2 | The use of N-substituted-5,6-dihydroxyindoles as a hair coloring agent | Bristol-Myers Squibb Company (US) | 1989-10-04 | — | — | EP | claimed |