Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 3/20 | 0.35 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508601 | 0.88 | SRC (0.42) | SRCNOX4PRKACAPRKACGPRKACB | |
| SCHEMBL9504714 | 0.85 | ALDH1A1 (0.41) | NOX4CDC7MAPTGAAALDH1A1 | |
| SCHEMBL9506012 | 0.82 | MAPT (0.34) | MAPTGAA | |
| SCHEMBL257518 | 0.72 | SLC6A2 (0.49) | CDC7MAPTALDH1A1PTK2 | |
| SCHEMBL9112610 | 0.71 | ALDH1A1 (0.51) | NOX4CDC7MAPTGAAALDH1A1 | |
| SCHEMBL31375351 | 0.68 | TYR (0.58) | GAAALDH1A1HPGDMAPK1 | |
| SCHEMBL28298713 | 0.68 | TYR (0.58) | GAAALDH1A1HPGDMAPK1 | |
| SCHEMBL48994 | 0.68 | TYR (0.58) | GAAALDH1A1HPGDMAPK1 | |
| SCHEMBL31375356 | 0.68 | TYR (0.58) | GAAALDH1A1HPGDMAPK1 | |
| SCHEMBL5659157 | 0.68 | BIRC5 (0.47) | CDC7MAPTALDH1A1TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335477-B1 | THE USE OF N-SUBSTITUTED-5,6-DIHYDROXYINDOLES AS A HAIR COLORING AGENT | Bristol-Myers Squibb Company (US) | 1993-07-21 | — | — | EP | claimed |