Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.46 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.45 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NHERF1 | O14745 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502834 | 0.89 | NPSR1 (0.46) | NPSR1SMN1; SMN2KMT2AMAPTRAB9A | |
| SCHEMBL9503597 | 0.85 | NPSR1 (0.44) | NPSR1KDM1ARCOR1SMN1; SMN2 | |
| SCHEMBL2635535 | 0.75 | PDK1 (0.54) | KDM1ARCOR1PDK1PDK2PDK3 | |
| SCHEMBL2971345 | 0.74 | MAPT (0.52) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL2282561 | 0.74 | SMN1; SMN2 (0.61) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL15828751 | 0.73 | MEN1 (0.55) | KDM1ARCOR1PDK1PDK2PDK3 | |
| SCHEMBL2279518 | 0.72 | PDK1 (0.54) | KDM1ARCOR1PDK1PDK2PDK3 | |
| SCHEMBL17150491 | 0.71 | PDK1 (0.56) | KDM1ARCOR1PDK1PDK2PDK3 | |
| SCHEMBL5335860 | 0.71 | KMT2A (0.62) | PDK1PDK2PDK3PDK4SMN1; SMN2 | |
| SCHEMBL2636652 | 0.71 | NPSR1 (0.61) | NPSR1PDK1PDK2PDK3PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |