Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504743 | 0.85 | NPSR1 (0.47) | NPSR1SMN1; SMN2KDM1ARCOR1 | |
| SCHEMBL9502834 | 0.84 | NPSR1 (0.46) | NPSR1SMN1; SMN2PPARG | |
| SCHEMBL9502840 | 0.71 | NPSR1 (0.54) | NPSR1SLC1A2SLC1A1PPARG | |
| SCHEMBL6108608 | 0.68 | SMN1; SMN2 (0.52) | SMN1; SMN2 | |
| SCHEMBL9815416 | 0.66 | RAB9A (0.63) | NPSR1SIRT2SIRT3MAOB | |
| SCHEMBL2720165 | 0.64 | MGAM (0.43) | — | |
| SCHEMBL4465319 | 0.64 | ALDH1A1 (0.56) | — | |
| SCHEMBL2717779 | 0.64 | POLB (0.40) | — | |
| SCHEMBL8930610 | 0.64 | RAB9A (0.44) | SLC1A2SLC1A1 | |
| SCHEMBL3475313 | 0.63 | ALDH1A1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0550574-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1993-07-14 | — | — | EP | disclosed |
| WO-1992005180-A1 | HETEROCYCLIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1992-04-02 | — | — | WO | disclosed |