Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2B | Q02880 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.48 |
| ▸ | FGB | P02675 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9504757 | 0.91 | TOP2B (0.60) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL23787705 | 0.80 | TERT (0.57) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL16343810 | 0.80 | MEN1 (0.55) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL31616803 | 0.80 | KMT2A (0.61) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL1903614 | 0.79 | MAPT (0.56) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL7112285 | 0.78 | KMT2A (0.62) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL3511311 | 0.78 | TOP2B (0.81) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL29843940 | 0.78 | TOP2B (0.81) | TOP2BNSD2FGBMMP14MAPT | |
| Hydrochloric Acid SCHEMBL9502000 | 0.78 | TOP2B (0.71) | TOP2BNSD2FGBMMP14MAPT | |
| SCHEMBL10781791 | 0.77 | MAPT (0.62) | TOP2BNSD2FGBMMP14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320960-B1 | AMINO ANTHRACENEDIONES-BIS PLATINUM COMPLEXES, USEFUL AS ANTITUMORAL AGENTS | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-05-12 | — | — | EP | disclosed |