Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.54 |
| ▸ | EEF2K | O00418 | 4/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9503601 | 0.80 | CYSLTR2 (0.48) | CYSLTR2CYSLTR1LARS1 | |
| SCHEMBL9560085 | 0.78 | CYSLTR2 (0.79) | CYSLTR2CYSLTR1 | |
| SCHEMBL10431544 | 0.74 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1CYP1A2CYP2C19 | |
| SCHEMBL9504777 | 0.73 | CYSLTR2 (0.57) | CYSLTR2CYSLTR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9506696 | 0.73 | CYSLTR2 (0.71) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560197 | 0.71 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1MCL1 | |
| SCHEMBL10482165 | 0.70 | CYSLTR2 (1.00) | CYSLTR2CYSLTR1 | |
| SCHEMBL9560077 | 0.70 | CYSLTR2 (0.69) | CYSLTR2CYSLTR1 | |
| SCHEMBL9505621 | 0.70 | CYSLTR2 (0.58) | CYSLTR2CYSLTR1TP53CYP1A2CYP3A4 | |
| SCHEMBL9506708 | 0.69 | CYSLTR2 (0.52) | CYSLTR2CYSLTR1TP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0375348-B1 | LEUKOTRIENE ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| US-4954513-A | Leukotriene antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1990-09-04 | — | — | US | disclosed |