Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.45 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.39 |
| ▸ | CLPP | Q16740 | 2/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9508171 | 0.79 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL7445918 | 0.76 | MEN1 (0.86) | KMT2AMEN1SMN1; SMN2ALDH1A1SCN1A | |
| Hydrogen Sulfide SCHEMBL28029146 | 0.74 | MEN1 (0.83) | KMT2AMEN1SMN1; SMN2ALDH1A1SCN1A | |
| SCHEMBL5951434 | 0.70 | BCAT2 (0.53) | KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL19435298 | 0.70 | MEN1 (0.63) | KMT2AMEN1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL17559748 | 0.70 | MEN1 (0.63) | KMT2AMEN1SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL2346836 | 0.69 | HNF4A (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2 | |
| Benzene SCHEMBL28175839 | 0.69 | HNF4A (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL30578395 | 0.69 | HNF4A (0.64) | KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2 | |
| SCHEMBL10029709 | 0.69 | BCAT2 (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0161939-B1 | ARYLHYDROXAMATES | E.R. Squibb & Sons, Inc. (US) | 1993-07-21 | — | — | EP | disclosed |
| CN-85104470-A | The method for preparing arythydroxamtes | — | 1986-10-01 | — | — | CN | disclosed |
| US-4607053-A | L2POXYGENASE INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1986-08-19 | — | — | US | disclosed |
| EP-0161939-A2 | Arylhydroxamates | E.R. Squibb & Sons, Inc. (US) | 1985-11-21 | — | — | EP | disclosed |