SCHEMBL9504895

SCHEMBL9504895

Cc1ccc(C(C)(OC(C)(c2ccc(C)cc2)c2ccc(C)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
ACHE P22303 6/20 0.44
TDP1 Q9NUW8 1/20 0.44
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
CA5A P35218 1/20 0.37
CYP19A1 P11511 1/20 0.35
BCHE P06276 1/20 0.35
ALDH1A1 P00352 2/20 0.35
CA7 P43166 1/20 0.35
MLYCD O95822 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KIF11 P52732 1/20 0.32
CYP3A4 P08684 1/20 0.32
TEAD4 Q15561 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504874 0.81 TSHR (0.62) TSHRACHETDP1NPC1MAPT
SCHEMBL21845090 0.78 TSHR (0.57) TSHRACHETDP1NPC1MAPT
SCHEMBL22556609 0.76 ESR1 (0.59) TSHRNPC1MAPTRAB9ACA1
SCHEMBL9507123 0.75 TSHR (0.48) TSHRACHETDP1NPC1MAPT
SCHEMBL7129049 0.74 MAPK1 (0.55) TSHRMAPTALDH1A1KMT2ACYP3A4
SCHEMBL6025165 0.74 TSHR (0.60) TSHRACHETDP1NPC1MAPT
SCHEMBL1442860 0.74 TSHR (0.52) TSHRACHETDP1NPC1MAPT
SCHEMBL9694917 0.74 TSHR (0.52) TSHRACHEALDH1A1MEN1KMT2A
SCHEMBL17273467 0.73 TSHR (0.67) TSHRACHETDP1NPC1MAPT
SCHEMBL18901114 0.73 TSHR (0.67) TSHRACHETDP1NPC1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0261962-B1 PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-07-28 EP disclosed
EP-0261962-A2 Process for producing propylene block copolymer MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-03-30 EP disclosed