Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | AGXT | P21549 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10534242 | 0.82 | TSHR (0.48) | TSHRNPC1MAPTRAB9AACHE | |
| SCHEMBL7614491 | 0.82 | TSHR (0.48) | TSHRNPC1MAPTRAB9AACHE | |
| SCHEMBL661183 | 0.79 | MAPK1 (0.46) | TSHRACHEALDH1A1KIF11CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL15899765 | 0.77 | MAPK1 (0.44) | TSHRACHEALDH1A1KIF11CYP3A4 | |
| SCHEMBL12139934 | 0.77 | TSHR (0.43) | TSHRNPC1MAPTRAB9AACHE | |
| SCHEMBL7607879 | 0.76 | TSHR (0.41) | TSHRNPC1MAPTRAB9AACHE | |
| SCHEMBL9504895 | 0.75 | TSHR (0.57) | TSHRNPC1MAPTRAB9AACHE | |
| SCHEMBL9504874 | 0.73 | TSHR (0.62) | TSHRNPC1MAPTRAB9AACHE | |
| SCHEMBL841033 | 0.72 | TSHR (0.39) | TSHRNPC1MAPTRAB9A | |
| SCHEMBL19543320 | 0.72 | KIF11 (0.47) | KMT2AMEN1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0261962-B1 | PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0261962-A2 | Process for producing propylene block copolymer | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1988-03-30 | — | — | EP | disclosed |