SCHEMBL9504874

SCHEMBL9504874

COC(C)(c1ccc(C)cc1)c1ccc(C)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.62
ACHE P22303 7/20 0.42
TDP1 Q9NUW8 2/20 0.42
NPC1 O15118 2/20 0.41
MAPT P10636 2/20 0.41
RAB9A P51151 2/20 0.41
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
CA5A P35218 1/20 0.35
LMNA P02545 2/20 0.35
TYR P14679 1/20 0.35
CYP19A1 P11511 1/20 0.34
BCHE P06276 1/20 0.34
ALDH1A1 P00352 2/20 0.33
CA7 P43166 1/20 0.33
RELA Q04206 1/20 0.33
MLYCD O95822 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9694917 0.91 TSHR (0.52) TSHRACHELMNAALDH1A1HPGD
SCHEMBL15730471 0.89 TSHR (0.50) TSHRACHENPC1MAPTRAB9A
SCHEMBL9504895 0.81 TSHR (0.57) TSHRACHETDP1NPC1MAPT
SCHEMBL7609864 0.79 TSHR (0.55) TSHRACHETDP1NPC1MAPT
SCHEMBL9508337 0.79 TSHR (0.55) TSHRACHETDP1NPC1MAPT
SCHEMBL166690 0.77 TSHR (1.00) TSHRACHETDP1NPC1MAPT
SCHEMBL5495871 0.77 TSHR (1.00) TSHRACHETDP1NPC1MAPT
P-Xylene SCHEMBL19859054 0.77 ACHE (0.53) TSHRACHETDP1CA1CA2
SCHEMBL17532646 0.77 MEN1 (0.52) TSHRACHENPC1MAPTRAB9A
SCHEMBL8584931 0.77 CYP2A6 (0.40) TSHRNPC1MAPTRAB9ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8551950-B2 Method of treatment or prophylaxis of inflammatory pain SPINIFEX PHARMACEUTICALS PTY LTD (AU) 2013-10-08 US disclosed
EP-0261962-B1 PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMER MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1993-07-28 EP disclosed
EP-0261962-A2 Process for producing propylene block copolymer MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1988-03-30 EP disclosed