SCHEMBL9504945

SCHEMBL9504945

CC(C)Cc1ccc(C(C)Oc2ccc(C(=O)Nc3c(OCCCC(=O)O)cccc3[N+](=O)[O-])cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 4/20 0.51
ADRA1D P25100 9/20 0.48
ADRA1A P35348 9/20 0.48
ADRA1B P35368 9/20 0.48
SRD5A1 P18405 3/20 0.45
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FFAR1 O14842 1/20 0.42
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PLK1 P53350 1/20 0.38
PLK3 Q9H4B4 1/20 0.38
GCG P01275 1/20 0.38
ALDH1A1 P00352 1/20 0.37
AKR1C3 P42330 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9504954 1.00 SRD5A2 (0.51) SRD5A2ADRA1DADRA1AADRA1BSRD5A1
SCHEMBL9504949 0.89 NPC1 (0.46) SRD5A2ADRA1DADRA1AADRA1BNPC1
SCHEMBL9507040 0.84 RAB9A (0.46) SRD5A2SRD5A1NPC1RAB9ASMN1; SMN2
SCHEMBL9347493 0.71 SRD5A2 (0.60) SRD5A2ADRA1DADRA1AADRA1BNPC1
SCHEMBL6489112 0.70 SERPINE1 (0.45) NPC1RAB9ASMN1; SMN2CYP1A2CYP3A4
SCHEMBL8159789 0.68 SRD5A2 (1.00) SRD5A2ADRA1DADRA1AADRA1BSRD5A1
SCHEMBL9597497 0.68 FFAR1 (0.56) SRD5A2SRD5A1FFAR1CYP2C9AKR1C3
SCHEMBL9336515 0.68 FFAR1 (0.56) SRD5A2SRD5A1FFAR1CYP2C9AKR1C3
SCHEMBL9347592 0.67 SRD5A2 (0.59) SRD5A2ADRA1DADRA1AADRA1BFFAR1
SCHEMBL9348949 0.67 ADRA1D (0.64) SRD5A2ADRA1DADRA1AADRA1BRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5140062-A None JP disclosed
JP-H05140062-A BENZOYLAMINOPHENOXY BUTANOATE DERIVATIVE AND MEDICAL DRUG CONTAINING THE SAME COMPOUND ONO PHARMACEUT CO LTD 1993-06-08 JP disclosed