Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250364 | 0.87 | KMT2A (0.49) | L3MBTL1CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL6489389 | 0.87 | L3MBTL1 (0.52) | L3MBTL1CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL6489977 | 0.84 | ALDH1A1 (0.49) | L3MBTL1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6501312 | 0.82 | L3MBTL1 (0.48) | L3MBTL1CYP2D6CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL5983525 | 0.81 | LMNA (0.51) | L3MBTL1CYP2C19CYP1A2CYP3A4MEN1 | |
| SCHEMBL27633714 | 0.81 | NPC1 (0.66) | L3MBTL1CYP2D6CYP2C19CYP1A2MEN1 | |
| SCHEMBL1137447 | 0.80 | CYP19A1 (0.59) | L3MBTL1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL7304281 | 0.77 | NPC1 (0.46) | SERPINE1L3MBTL1CYP2D6CYP2C19MEN1 | |
| SCHEMBL3449044 | 0.77 | ALDH1A1 (0.56) | L3MBTL1CYP3A4MEN1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL7312489 | 0.76 | NPC1 (0.44) | SERPINE1L3MBTL1CYP2D6CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| WO-2004108686-A2 | BENZIMIDAZOLE COMPOUNDS HAVING HYPOGLYCEMIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014812-A1 | Benzimidazole compounds | SLC5A1, SLC5A2, G6PD | SERPINE1 1113/4885L3MBTL1 790/4885CYP2D6 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.