SCHEMBL9504970

SCHEMBL9504970

C=CCc1ccc(-c2ccc(CC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
TP53 P04637 3/20 0.52
CYP3A4 P08684 2/20 0.52
SMN1; SMN2 Q16637 2/20 0.52
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ALOX12 P18054 1/20 0.52
PPARG P37231 2/20 0.42
PPARD Q03181 2/20 0.42
PPARA Q07869 1/20 0.42
XDH P47989 1/20 0.42
GABRA1 P14867 5/20 0.41
GABRB2 P47870 5/20 0.41
CNR2 P34972 4/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 2/20 0.41
GAA P10253 2/20 0.41
CNR1 P21554 2/20 0.41
KMT2A Q03164 2/20 0.41
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556361 0.93 ALDH1A1 (0.58) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL584333 0.88 ALDH1A1 (0.56) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
Water SCHEMBL28100235 0.85 ALDH1A1 (0.54) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL6513657 0.83 ALDH1A1 (0.48) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
Allylbenzene SCHEMBL11226285 0.82 TP53 (0.64) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL24125046 0.82 KIF11 (0.39) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL19084220 0.81 SMN1; SMN2 (0.62) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL3791364 0.80 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL173301 0.80 ALDH1A1 (0.64) ALDH1A1TP53CYP3A4SMN1; SMN2ALOX15
SCHEMBL2776957 0.80 TP53 (0.56) ALDH1A1TP53SMN1; SMN2TSHRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5140004-A None JP disclosed
JP-H05140004-A PRODUCTION OF ETHYL-SUBSTITUTED BIPHENYL COMPOUNDS NIPPON PETROCHEM CO LTD 1993-06-08 JP disclosed