SCHEMBL6513657

SCHEMBL6513657

C=CCc1ccc(-c2ccc(CCC)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
TP53 P04637 1/20 0.48
CYP3A4 P08684 1/20 0.48
ALOX15 P16050 1/20 0.48
TSHR P16473 1/20 0.48
ALOX12 P18054 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
THRB P10828 2/20 0.47
MCL1 Q07820 1/20 0.41
LPL P06858 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
CNR2 P34972 4/20 0.40
PPARG P37231 2/20 0.40
PPARD Q03181 2/20 0.40
PPARA Q07869 1/20 0.40
ALOX5 P09917 3/20 0.40
NISCH Q9Y2I1 1/20 0.40
XDH P47989 1/20 0.39
HRH3 Q9Y5N1 1/20 0.39
MAPT P10636 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2553722 0.94 ALDH1A1 (0.54) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL584333 0.84 ALDH1A1 (0.56) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL20058177 0.83 THRB (0.47) TSHRTHRBMCL1LPLLIPG
SCHEMBL24125045 0.83 RARB (0.43) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL9504970 0.83 ALDH1A1 (0.52) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL9617250 0.82 ACACB (0.44) ALDH1A1TP53CYP3A4ALOX15TSHR
Water SCHEMBL28100235 0.82 ALDH1A1 (0.54) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL4802707 0.82 LPL (0.54) TSHRMCL1LPLLIPGCNR2
SCHEMBL7188791 0.81 THRB (0.55) ALDH1A1TP53CYP3A4ALOX15TSHR
SCHEMBL8857437 0.81 ALDH1A1 (0.45) ALDH1A1TP53CYP3A4ALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050101063-A1 Three-terminal field-controlled molecular devices TOUR JAMES M (US) 2005-05-12 US disclosed
WO-2002035580-A2 THREE-TERMINAL FIELD-CONTROLLED MOLECULAR DEVICES MOLECULAR ELECTRONICS CORPORATION (US) 2002-05-02 WO disclosed