Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | APP | P05067 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 5/20 | 0.54 |
| ▸ | CA2 | P00918 | 5/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL7630477 | 1.00 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Sulfuric Acid SCHEMBL29722524 | 0.89 | NR4A1 (0.79) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Sulfuric Acid SCHEMBL11419340 | 0.89 | NR4A1 (0.79) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL11052026 | 0.88 | ALDH1A1 (0.69) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL22462568 | 0.86 | TDP1 (0.73) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Trifluoromethanesulfonic Acid SCHEMBL4812154 | 0.86 | TDP1 (0.59) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Hydrogen Peroxide SCHEMBL7094445 | 0.85 | TDP1 (0.89) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Methyl Alcohol SCHEMBL11502051 | 0.85 | TDP1 (0.89) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| Methyl Alcohol SCHEMBL27721382 | 0.85 | TDP1 (0.89) | TDP1MAPK1ALDH1A1CYP3A4APP | |
| SCHEMBL5097 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272212-B1 | PROCESS FOR CONTINUALLY PRODUCING AZO OR HYDRAZONE DYES | CIBA-GEIGY AG (CH) | 1993-09-01 | — | — | EP | disclosed |
| EP-0272212-A2 | Process for continually producing azo or hydrazone dyes | CIBA-GEIGY AG (CH) | 1988-06-22 | — | — | EP | disclosed |