Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL4812154

COc1ccc(N)cc1.O=S(=O)(O)C(F)(F)F

nearest known ligand 0.59

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
MAPK1 P28482 1/20 0.59
ALDH1A1 P00352 3/20 0.57
CYP3A4 P08684 1/20 0.57
APP P05067 2/20 0.48
NR4A1 P22736 1/20 0.48
CA1 P00915 5/20 0.46
CA2 P00918 5/20 0.46
CA9 Q16790 2/20 0.46
HSD11B1 P28845 1/20 0.44
PKM P14618 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 1/20 0.42
NPC1 O15118 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL9505045 0.86 TDP1 (0.73) TDP1MAPK1ALDH1A1CYP3A4APP
Sulfuric Acid SCHEMBL7630477 0.86 TDP1 (0.73) TDP1MAPK1ALDH1A1CYP3A4APP
Mequinol SCHEMBL8898999 0.83 PKM (0.61) ALDH1A1APPCA1CA2CA9
SCHEMBL22462568 0.82 TDP1 (0.73) TDP1MAPK1ALDH1A1CYP3A4APP
Trifluoromethanesulfonic Acid SCHEMBL27825973 0.81 CA1 (0.46) ALDH1A1CA1CA2CA9HSD11B1
Trifluoromethanesulfonic Acid SCHEMBL18306126 0.81 APP (0.44) ALDH1A1APPCA1CA2CA9
Trifluoromethanesulfonic Acid SCHEMBL1859837 0.81 APP (0.44) ALDH1A1APPCA1CA2CA9
Trifluoromethanesulfonic Acid SCHEMBL3385544 0.81 HSD11B1 (0.44) ALDH1A1CA1CA2CA9HSD11B1
Anisole SCHEMBL4551224 0.81 CA4 (0.56) CA1CA2HSD11B1PKMGAA
Trifluoromethanesulfonic Acid SCHEMBL28499316 0.81 MAOB (0.51) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107513015-B Method for preparing 3-benzoyl ethyl acrylate from enalapril intermediate synthesis mother liquor 浙江工业大学 2020-11-06 CN claimed
US-7351849-B2 Process for producing optically active β-amino acid derivatives TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-04-01 US disclosed
US-20060205968-A1 Process for producing optically active beta-amino acid derivatives TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-09-14 US disclosed
EP-1656342-A2 PROCESS FOR PRODUCING OPTICALLY ACTIVE BETA-AMINO ACID DERIVATIVES Takasago International Corporation (JP) 2006-05-17 EP disclosed
WO-2005016866-A2 PROCESS FOR PRODUCING OPTICALLY ACTIIVE BETA-AMINO ACID DERIVATIVES TAKASAGO INTERNATIONAL CORPORATION (JP) 2005-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060205968-A1 Process for producing optically active beta-amino acid derivatives BCAT1, ALAD, AADAT TDP1 4754/4885MAPK1 838/4885ALDH1A1 148/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.