SCHEMBL9505056

SCHEMBL9505056

Cc1csc(Oc2ccc(C(C)Br)cc2)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9473980 0.76 SLC6A4 (0.40) ALDH1A1SMN1; SMN2
SCHEMBL11737701 0.75 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2
SCHEMBL4730671 0.75 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2
SCHEMBL9473089 0.75 ST14 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL9502056 0.71 TTR (0.37) ALDH1A1SMN1; SMN2
SCHEMBL9474057 0.71 LTA4H (0.47)
SCHEMBL920207 0.71 ST14 (0.53) ALDH1A1SMN1; SMN2
SCHEMBL2962405 0.71 AR (0.46) ALDH1A1SMN1; SMN2
SCHEMBL9264476 0.71 ALDH1A1 (0.46) ALDH1A1SMN1; SMN2
SCHEMBL9453084 0.71 DAO (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0186190-B1 BENZIMIDAZOLE DERIVATIVES, AND THEIR PRODUCTION AND USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-26 EP disclosed
US-4663339-A Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-05-05 US disclosed