Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31674385 | 0.85 | ABCC4 (0.32) | — | |
| Glycinebetaine SCHEMBL9505082 | 0.81 | — | — | |
| SCHEMBL28356203 | 0.67 | — | — | |
| Glycinebetaine SCHEMBL1617824 | 0.66 | TSHR (0.42) | — | |
| Hydrochloric Acid SCHEMBL28576356 | 0.66 | — | — | |
| Glycinebetaine SCHEMBL9506376 | 0.64 | — | — | |
| Glycine SCHEMBL28849450 | 0.64 | APP (0.33) | — | |
| Glycinebetaine SCHEMBL3497624 | 0.64 | TSHR (0.46) | — | |
| Glycinebetaine SCHEMBL2520108 | 0.63 | LMNA (0.46) | — | |
| Adipic Acid SCHEMBL5474223 | 0.63 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0250887-B1 | INTERNALLY CROSSLINKED POLYMER MICROPARTICLES HAVING THREE-DIMENSIONAL NETWORK STRUCTURE | Nippon Paint Co., Ltd. (JP) | 1993-08-25 | — | — | EP | claimed |
| EP-0250887-B1 | INTERNALLY CROSSLINKED POLYMER MICROPARTICLES HAVING THREE-DIMENSIONAL NETWORK STRUCTURE | Nippon Paint Co., Ltd. (JP) | 1993-08-25 | — | — | EP | disclosed |
| US-5064923-A | CROSSLINKED POLYMER MICROPARTICLES DERIVED FROM BETAINE MONOMERS HAVING THREE-DIMENSIONAL NETWORK | NIPPON PAINT CO., LTD. (JP) | 1991-11-12 | — | — | US | disclosed |
| EP-0250887-A2 | Internally crosslinked polymer microparticles having three-dimensional network structure | Nippon Paint Co., Ltd. (JP) | 1988-01-07 | — | — | EP | disclosed |