Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5854929 | 0.86 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL5854934 | 0.86 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL10475396 | 0.85 | CACNA1B (0.74) | CACNA1BADORA3 | |
| SCHEMBL10475395 | 0.81 | ALDH1A1 (0.78) | CACNA1BADORA3 | |
| SCHEMBL29173863 | 0.81 | ADORA3 (0.82) | CACNA1BADORA3 | |
| SCHEMBL5856485 | 0.81 | CACNA1B (0.89) | CACNA1B | |
| SCHEMBL5856492 | 0.81 | CACNA1B (0.89) | CACNA1B | |
| SCHEMBL9505249 | 0.79 | ALDH1A1 (0.67) | CACNA1BADORA3 | |
| SCHEMBL5855595 | 0.79 | CACNA1B (0.85) | CACNA1B | |
| SCHEMBL5856555 | 0.79 | CACNA1B (0.85) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0458823-B1 | A PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5245039-A | PROCESS FOR PREPARATION OF ENANTIOMERICALLY PURE POLYSUBSTITUTED 1,4-DIHYDROPYRIDINES | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-09-14 | — | — | US | disclosed |
| EP-0383320-A1 | A process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1990-08-22 | — | — | EP | disclosed |