Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CUL4A | Q13619 | 2/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.33 |
| ▸ | CCNH | P51946 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11353190 | 0.85 | KMT2A (0.36) | CUL4ATDP1CDK1CCNB1CCNA2 | |
| SCHEMBL27293417 | 0.84 | TRPV4 (0.33) | TRPV4TDP1CDK1CCNB1CCNA2 | |
| SCHEMBL10805519 | 0.80 | GAA (0.32) | CUL4ATRPV4MAPTPKMKDM4E | |
| SCHEMBL11350166 | 0.75 | CUL4A (0.42) | CUL4ATRPV4CA12CA1CA2 | |
| SCHEMBL3016567 | 0.74 | MAPT (0.40) | TRPV4TDP1CDK1CCNB1CCNA2 | |
| SCHEMBL14165763 | 0.73 | LMNA (0.35) | TRPV4MAPTKDM4ELMNA | |
| SCHEMBL11348961 | 0.72 | TDP1 (0.40) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL27298174 | 0.70 | PKM (0.33) | TRPV4CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL8028531 | 0.68 | PKM (0.33) | TDP1CDK1CCNB1CCNA2CCND1 | |
| SCHEMBL10591189 | 0.67 | DAO (0.44) | TDP1CDK1CCNB1CCNA2CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0340472-B1 | PROCESS FOR THE PREPARATION OF 5-CHLORO-3-CHLOROSULPHONYL-2-THIOPHENE-CARBOXYLIC ESTERS | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1993-07-28 | — | — | EP | disclosed |
| EP-0340472-A1 | Process for the preparation of 5-chloro-3-chlorosulphonyl-2-thiophene-carboxylic esters | Hafslund Nycomed Pharma Aktiengesellschaft (AT) | 1989-11-08 | — | — | EP | disclosed |