Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.47 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.47 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446475 | 0.84 | TDP1 (0.55) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL3656487 | 0.81 | TDP1 (0.52) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL17704246 | 0.81 | TDP1 (0.52) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL18925062 | 0.78 | TDP1 (0.49) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL11833322 | 0.77 | TDP1 (0.50) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL4747577 | 0.77 | TDP1 (0.55) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL8147133 | 0.77 | ALDH1A1 (0.58) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL3592382 | 0.76 | TDP1 (0.63) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL18924913 | 0.76 | TDP1 (0.46) | TDP1POLBALDH1A1MAPK1GPR35 | |
| SCHEMBL14211045 | 0.76 | TDP1 (0.49) | TDP1POLBALDH1A1MAPK1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0328968-B1 | PROCESS FOR THE PREPARATION OF 4-ACYLAMINO-2-AMINO ALKOXY BENZENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0328968-A2 | Process for the preparation of 4-acylamino-2-amino alkoxy benzenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-23 | — | — | EP | disclosed |